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Featured Treatment Options

Marcellus Health Concierge Services

22 West 48th Street Suit# 300, Manhattan, NY, 10036

www.zocdoc.com/doctor/jean-jeffrey-marcellus-np-300519

Marcellus Health Concierge Services, an affiliate of Ascendant New York and Thrivee (Now Kaden) discreetly and privately provides help for those dealing with the difficulties assoc... More

iRecovery

(561) 464-5500

2900 N. Military Trail ,Ste. 241, Boca Raton, FL, 33431

irecoveryusa.com/

iRecovery has a team of licensed experts to provide private, affordable, and accessible drug and alcohol treatment from the safety of your home v... More

R. Sinha, MD

(614) 534-1100

2735 Sawbury Blvd, Columbus, OH, 43235
www.buckeyeclinic.com/

Addiction Recovery Provider. We accept Medicare, Medicaid, Caresource, Molina and others insurance. Please call to confirm.... More

Detox With Dignity

(770) 559-9554

11800 Northfall Lane ,#1406, Alpharetta, GA, 30009
www.detoxwithdignityga.com/

Out patient treatment for addiction to Heroin, methadone, oxycodone, kratom, and other painkilers. Treatment with suboxone, Sublacade, Probuphine and subutex and other buprenorphi... More

Spero Health

(513) 880-0016

5966 Boymel Drive, Fairfield, OH, 45014
sperohealth.com/

Spero Health, Inc., is an integrated healthcare services organization specializing in local and affordable outpatient care for individuals suffering from substance use disorders wi... More

Spero Health

(937) 203-4928

7271 North Main Street, Dayton, OH, 45415
sperohealth.com/

Spero Health, Inc., is an integrated healthcare services organization specializing in local and affordable outpatient care for individuals suffering from substance use disorders wi... More

Spero Health

(615) 751-0579

301 Wolverine Trail Suite 200, Smyrna, TN, 37176
sperohealth.com/

Spero Health, Inc., is an integrated healthcare services organization specializing in local and affordable outpatient care for individuals suffering from substance use disorders wi... More

Spero Health

(901) 302-9532

920 Estate Drive, Memphis, TN, 38119
sperohealth.com/

Spero Health, Inc., is an integrated healthcare services organization specializing in local and affordable outpatient care for individuals suffering from substance use disorders wi... More

Spero Health

(731) 201-5590

172 West University Parkway, Jackson, TN, 38305
sperohealth.com/

Spero Health, Inc., is an integrated healthcare services organization specializing in local and affordable outpatient care for individuals suffering from substance use disorders wi... More

Spero Health

(731) 334-5390

433 East Parkview Street, Dyersburg, TN, 38024
sperohealth.com/

Spero Health, Inc., is an integrated healthcare services organization specializing in local and affordable outpatient care for individuals suffering from substance use disorders wi... More

Additional Treatment Options

Signature Psychiatric Hospital

2900 Clay Edwards Drive, North Kansas City, MO, 64116

Phone: 833-452-1918

Shelby Comprehensive Treatment Center

1895 East Dixon Blvd., Shelby, NC, 28152

Phone: 844-670-3389

Seymour Comprehensive Treatment Center

357 Tanger Blvd, Seymour, IN, 47272

Phone: 833-457-1137

River Place Behavioral Health Hospital

500 Rue de Sante, LaPlace, LA, 70068

Phone: 877-794-9517

North Miami Comprehensive Treatment Center

12700 West Dixie Hwy, North Miami, FL, 33161

Phone: 833-601-1529

Mount Carmel Behavioral Health

4646 Hilton Corporate Drive, Columbus, OH, 43232

Phone: 844-670-3239

Pinnacle Point Counseling/Recovery Coach

Book Online, Tampa, FL, 33613

Phone: 8135305216

Montrose Behavioral Health Hospital for Kids

4720 North Clarendon Avenue, Chicago, IL, 60640

Phone: 877-374-2407

Montrose Behavioral Health Hospital

4840 North Marine Drive, Chicago, IL, 60640

Phone: 877-794-9517

Maple Heights Behavioral Health

3955 West Washington Center Road, Fort Wayne, IN, 46818

Phone: 877-480-5873

Lynnwood Comprehensive Treatment Center

2322 196th Street SW, Lynnwood, WA, 98036

Phone: 888-907-1088

Loganville Comprehensive Treatment Center

3543 Highway 81, Loganville, GA, 30052

Phone: 866-389-2356

Life Center of Hillsville

160 Training Center Rd, Hillsville, VA, 24343

Phone: 276-779-6470

Lakeland Comprehensive Treatment Center

1510 Commercial Park Drive, Lakeland, FL, 33801

Phone: 844-539-1060

Kenosha Comprehensive Treatment Center

7991 Sheridan Road, Kenosha, WI, 53143

Phone: 888-984-3023

Geisinger Behavioral Health Center Northeast

60 Glenmaura National Boulevard, Moosic, PA, 18507

Phone: 888-989-4342

Ft. Lauderdale Comprehensive Treatment Center

5481 N State Road 7, Ft. Lauderdale, FL, 33319

Phone: 888-463-0382

East Tennessee Behavioral Health

1444 Old Weisgarber Road, Knoxville, TN, 37909

Phone: 866-394-2605

Dover Comprehensive Treatment Center

429 S New Street, Dover, DE, 19904

Phone: 866-948-1683

Dallas Comprehensive Treatment Center

311 W I Parkway, Dallas, GA, 30132

Phone: 877-418-1547

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INDICATION AND IMPORTANT SAFETY INFORMATION

WHAT IS BRIXADI?

BRIXADI is a prescription medicine used to treat moderate to severe opioid addiction (dependence) to opioid drugs (prescription or illegal) in people who have started treatment with a single dose of a buprenorphine medicine in the form of a sublingual tablet or buccal film (transmucosal), or who are already being treated with buprenorphine. BRIXADI should be used as part of a complete treatment plan that also includes counseling and behavioral therapy.

IMPORTANT SAFETY INFORMATION

What is the most important information I should know about BRIXADI?

Because of the serious risk of potential harm or death from self-injecting BRIXADI into a vein (intravenously), it is only available through a restricted program called the BRIXADI Risk Evaluation and Mitigation Strategy (REMS) Program.

BRIXADI is not available in retail pharmacies.

Your BRIXADI injection will only be given to you by a healthcare provider.

BRIXADI (buprenorphine) extended-release injection for subcutaneous use contains a medicine called buprenorphine. Buprenorphine is an opioid that can cause serious and life-threatening breathing problems, especially if you take or use certain other medicines or drugs.

Talk to your healthcare provider about naloxone. Naloxone is a medicine that is available to patients for the emergency treatment of an opioid overdose. If naloxone is given, you must call 911 or get emergency medical help right away to treat an overdose or accidental use of an opioid.

BRIXADI can cause serious and life-threatening breathing problems. Get emergency help right away if you feel faint, feel dizzy, are confused, feel sleepy or uncoordinated, have blurred vision, have slurred speech, are breathing slower than normal, or cannot think well or clearly.

Do not take BRIXADI with certain medicines. Taking BRIXADI with other opioid medicines, benzodiazepines, alcohol, other central nervous system depressants (including street drugs) can cause severe drowsiness, decreased awareness, breathing problems, coma, and death.

In an emergency, have family members tell the emergency department staff that you are physically dependent on an opioid and are being treated with BRIXADI.

You may have detectable levels of BRIXADI in your body for several months after stopping treatment with BRIXADI.

Do not receive BRIXADI if you are allergic to buprenorphine or any ingredients in BRIXADI:

BRIXADI weekly: anhydrous ethanol, soybean phosphatidylcholine, glycerol dioleate

BRIXADI monthly: N-methylpyrrolidone, soybean phosphatidylcholine, glycerol dioleate

Before receiving BRIXADI, tell your healthcare provider about all of your medical conditions, including if you have:

Trouble breathing or lung problems

A curve in your spine that affects your breathing

Addison’s disease

An enlarged prostate (men)

Problems urinating

Liver, kidney, or gallbladder problems

A history of alcoholism

A head injury or brain problem

Mental health problems

Adrenal gland or thyroid gland problems

A latex allergy. The BRIXADI needle cap contains latex.

Tell your healthcare provider if you are:

pregnant or plan to become pregnant. If you receive BRIXADI while pregnant, your baby may have symptoms of opioid withdrawal at birth that could be life-threatening if not recognized and treated. Talk to your healthcare provider if you are pregnant or become pregnant.

breastfeeding. BRIXADI can pass into your breast milk and may harm your baby. Talk to your healthcare provider about the best way to feed your baby during treatment with BRIXADI. Monitor your baby for increased drowsiness and breathing problems if you breastfeed during treatment with BRIXADI.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Talk with your healthcare provider before starting any new medicines during or after stopping treatment with BRIXADI.

What should I avoid while receiving BRIXADI?

Do not drive, operate heavy machinery or perform any other dangerous activities until you know how BRIXADI affects you. BRIXADI can cause drowsiness and slow reaction times. BRIXADI can make you sleepy, dizzy, or lightheaded. This may happen more often in the first few days after your injection and when your dose is being changed.

You should not drink alcohol or use prescription or over-the-counter medicines that contain alcohol during treatment with BRIXADI, because this can lead to loss of consciousness or even death.

What are the possible side effects of BRIXADI?

BRIXADI can cause serious side effects, including:

Trouble breathing. Taking BRIXADI with other opioid medicines, benzodiazepines, alcohol, or other central nervous system depressants can cause breathing problems that can lead to coma and death.

Sleepiness, dizziness, and problems with coordination.

Physical dependence or abuse.

Liver problems. Call your healthcare provider right away if you notice any of these symptoms:

your skin or the white part of your eyes turns yellow (jaundice)

dark or “tea-colored” urine

light-colored stools (bowel movements)

loss of appetite

pain, aching, or tenderness on the right side of your stomach area

nausea

Your healthcare provider should do tests to check your liver before and during treatment with BRIXADI.

Allergic reaction. You may have a rash, hives, swelling of your face, wheezing, light-headedness when changing positions, feeling faint, or loss of consciousness. Call your healthcare provider or get emergency help right away.

Opioid withdrawal. Call your healthcare provider right away if you get any of these symptoms:

shaking

sweating more than normal

feeling hot or cold more than normal

runny nose

watery eyes

goose bumps

diarrhea

vomiting

muscle aches

These symptoms may start weeks to months after your last dose of BRIXADI. Tell your healthcare provider if you develop any of these symptoms.

Decrease in blood pressure. You may feel dizzy if you get up too fast from sitting or lying down.

The most common side effects of BRIXADI include: injection site pain, headache, constipation, nausea, injection site redness, injection site itching, trouble sleeping (insomnia), and urinary tract infection.

BRIXADI may affect fertility in males and females. Talk to your healthcare provider if this is a concern for you.

These are not all the possible side effects of BRIXADI. Call your healthcare provider for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1‑800‑FDA‑1088.

For more information about BRIXADI, ask your healthcare provider or go to www.BRIXADI.com or call 1-833-274-9234.

This information does not take the place of talking with your healthcare provider for medical advice about your condition or treatment.

All registered trademarks are the property of their respective owners.
© 2025 Braeburn Inc. All rights reserved.
Plymouth Meeting, PA 19462
BRX-1509/June 2025
www.braeburnrx.com

Please see BRIXADI Medication Guide and Full Prescribing Information, including BOXED WARNING.

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Featured Treatment Options

Marcellus Health Concierge Services

iRecovery

R. Sinha, MD

Detox With Dignity

Spero Health

Spero Health

Spero Health

Spero Health

Spero Health

Spero Health

Additional Treatment Options

Signature Psychiatric Hospital

Shelby Comprehensive Treatment Center

Seymour Comprehensive Treatment Center

River Place Behavioral Health Hospital

North Miami Comprehensive Treatment Center

Mount Carmel Behavioral Health

Pinnacle Point Counseling/Recovery Coach

Montrose Behavioral Health Hospital for Kids

Montrose Behavioral Health Hospital

Maple Heights Behavioral Health

Lynnwood Comprehensive Treatment Center

Loganville Comprehensive Treatment Center

Life Center of Hillsville

Lakeland Comprehensive Treatment Center

Kenosha Comprehensive Treatment Center

Geisinger Behavioral Health Center Northeast

Ft. Lauderdale Comprehensive Treatment Center

East Tennessee Behavioral Health

Dover Comprehensive Treatment Center

Dallas Comprehensive Treatment Center

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